.Pharmacolibrary.Drugs.ATC.J.J01XA05 .Pharmacolibrary.Drugs.ATC.J.J01XA05| name: | Oritavancin |
| ATC code: | J01XA05 | route: | intravenous |
| n-compartments | 3 |
Oritavancin is a semisynthetic lipoglycopeptide antibiotic used for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It is approved for use in adults and is administered as a single intravenous dose.
Population pharmacokinetics in healthy adult subjects receiving a single intravenous dose.
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Dunbar, LM, et al., & Wasilewski, MM (2011). Comparison of the efficacy and safety of oritavancin front-loaded dosing regimens to daily dosing: an analysis of the SIMPLIFI trial. Antimicrobial agents and chemotherapy 55(7) 3476–3484. DOI:10.1128/AAC.00029-11 PUBMED:https://pubmed.ncbi.nlm.nih.gov/21537018