name: | SodiumAminosalicylate |
ATC code: | J04AA02 | route: | oral |
n-compartments | 1 |
Sodium aminosalicylate (para-aminosalicylic acid, PAS) is an antibiotic primarily used for the treatment of tuberculosis. It acts as a bacteriostatic agent by inhibiting folic acid synthesis in Mycobacterium tuberculosis. Previously a first-line agent in tuberculosis therapy, it is now mainly used as a second-line drug, especially for multidrug-resistant tuberculosis, owing to the availability of more effective agents. It is not widely used today except in resistant cases.
Pharmacokinetic parameters reported in healthy adults after oral administration.