.Pharmacolibrary.Drugs.ATC.J.J04AM03 .Pharmacolibrary.Drugs.ATC.J.J04AM03| name: | EthambutolAndIsoniazid | |
| ATC code: | J04AM03 | route: | oral |
| compartments: | 1 | |
| dosage: | 400 | mg |
| volume of distribution: | 56 | L |
| clearance: | 81 | L/h |
| other parameters in model implementation | ||
Ethambutol and isoniazid is a fixed combination antituberculosis medication used primarily for the treatment of tuberculosis. Ethambutol acts by inhibiting cell wall synthesis, while isoniazid is a prodrug that inhibits the synthesis of mycolic acids. This combination is approved and widely used as part of multi-drug regimens for the treatment of tuberculosis.
Population pharmacokinetics of ethambutol and isoniazid in adult patients with tuberculosis, administered orally as fixed-dose combination tablets.