.Pharmacolibrary.Drugs.ATC.J.J05AB09

Information

name:Famciclovir
ATC code:J05AB09
route:oral
n-compartments1

Famciclovir is an oral prodrug of penciclovir, an antiviral agent used primarily for the treatment of herpes zoster (shingles) and herpes simplex virus infections. It is approved for use in adults and adolescents and is widely used today.

Pharmacokinetics

Pharmacokinetic parameters derived from healthy adult subjects following a single oral dose of famciclovir 500 mg.

References

  1. Schenkel, F, et al., & Daali, Y (2013). Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic model. The Journal of antimicrobial chemotherapy 68(7) 1635–1641. DOI:10.1093/jac/dkt064 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23539240

  2. Ogungbenro, K, et al., & Aarons, L (2009). Population pharmacokinetics and optimal design of paediatric studies for famciclovir. British journal of clinical pharmacology 68(4) 546–560. DOI:10.1111/j.1365-2125.2009.03479.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/19843058

  3. Blumer, J, et al., & Hamed, K (2010). Single-dose pharmacokinetics of famciclovir in infants and population pharmacokinetic analysis in infants and children. Antimicrobial agents and chemotherapy 54(5) 2032–2041. DOI:10.1128/AAC.01508-09 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20160046

Revisions


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