.Pharmacolibrary.Drugs.ATC.J.J05AF12 .Pharmacolibrary.Drugs.ATC.J.J05AF12| name: | Clevudine | |
| ATC code: | J05AF12 | route: | oral |
| compartments: | 1 | |
| dosage: | 30 | mg |
| volume of distribution: | 75 | L |
| clearance: | 16 | L/h |
| other parameters in model implementation | ||
Clevudine is a nucleoside analog antiviral drug primarily developed for the treatment of chronic hepatitis B virus (HBV) infection. It inhibits DNA synthesis of HBV by acting as a reverse transcriptase inhibitor. Clevudine is not currently approved for use in the United States or many other major markets, but was approved and used in certain Asian countries.
Pharmacokinetic parameters reported for adult healthy volunteers and patients with chronic hepatitis B following oral administration.