.Pharmacolibrary.Drugs.ATC.J.J05AG02 .Pharmacolibrary.Drugs.ATC.J.J05AG02| name: | Delavirdine |
| ATC code: | J05AG02 | route: | oral |
| n-compartments | 1 |
Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used as part of combination antiretroviral therapy for the treatment of HIV-1 infection. Its clinical use has largely diminished in favor of newer agents due to lower efficacy and higher rates of drug interactions; it is no longer recommended in current treatment guidelines and is not widely used or available today.
Pharmacokinetics reported in HIV-infected adult patients after single and multiple oral doses. Main data from clinical trials, studies include both male and female adults with HIV infection.
Smith, PF, et al., & Morse, GD (2005). Population pharmacokinetics of delavirdine and N-delavirdine in HIV-infected individuals. Clinical pharmacokinetics 44(1) 99–109. DOI:10.2165/00003088-200544010-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15634033