name: | Nelarabine |
ATC code: | L01BB07 | route: | intravenous |
n-compartments | 2 |
Nelarabine is a prodrug of the deoxyguanosine analogue ara-G, approved for the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) in both pediatric and adult patients. It is used when the disease has not responded to, or has relapsed following, at least two chemotherapy regimens.
Pharmacokinetic parameters in adults and pediatric patients with refractory or relapsed T-cell acute lymphoblastic leukemia or T-cell lymphoblastic lymphoma following intravenous administration.