.Pharmacolibrary.Drugs.ATC.L.L01CA06 .Pharmacolibrary.Drugs.ATC.L.L01CA06| name: | Vintafolide | |
| ATC code: | L01CA06 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 2.5 | mg |
| volume of distribution: | 5.5 | L |
| clearance: | 0.95 | L/h |
| other parameters in model implementation | ||
Vintafolide is a folate–drug conjugate developed for targeted cancer therapy, mainly investigated for the treatment of folate receptor-positive solid tumors such as ovarian cancer. It is not currently approved for clinical use after phase III trials failed to meet endpoints.
Estimated pharmacokinetic parameters for adult cancer patients, as no published human PK data are available.