name: | Lenvatinib |
ATC code: | L01EX08 | route: | oral |
n-compartments | 2 |
Lenvatinib is a multi-kinase inhibitor indicated for the treatment of certain types of cancer, including differentiated thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma. It is an oral anticancer drug currently approved for use in several regions including the US and EU.
Population pharmacokinetic analysis in patients with advanced solid tumors, administered orally, typical adult population.
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Wei, Y, et al., & Zhang, X (2023). Effects of diet and gender on the pharmacokinetics of oral lenvatinib: A clinical trial in healthy Chinese participants. International journal of clinical pharmacology and therapeutics 61(11) 475–481. DOI:10.5414/CP204440 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37644876
Gupta, A, et al., & Hussein, Z (2016). Population pharmacokinetic analysis of lenvatinib in healthy subjects and patients with cancer. British journal of clinical pharmacology 81(6) 1124–1133. DOI:10.1111/bcp.12907 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26879594