.Pharmacolibrary.Drugs.ATC.L.L01XX53 .Pharmacolibrary.Drugs.ATC.L.L01XX53| name: | Vosaroxin | |
| ATC code: | L01XX53 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 72 | mg |
| volume of distribution: | 112 | L |
| clearance: | 4.8 | L/h |
| other parameters in model implementation | ||
Vosaroxin is an experimental anticancer quinolone derivative acting as a topoisomerase II inhibitor. It was being developed for the treatment of acute myeloid leukemia (AML) but is not approved for use; development was discontinued after phase III trials did not meet efficacy endpoints.
Pharmacokinetic parameters in adult patients with relapsed or refractory acute myeloid leukemia after intravenous administration.