.Pharmacolibrary.Drugs.ATC.L.L01XX77 .Pharmacolibrary.Drugs.ATC.L.L01XX77| name: | Adagrasib | |
| ATC code: | L01XX77 | route: | oral |
| compartments: | 2 | |
| dosage: | 600 | mg |
| volume of distribution: | 167 | L |
| clearance: | 26.8 | L/h |
| other parameters in model implementation | ||
Adagrasib is an orally active, irreversible KRAS G12C inhibitor used in the treatment of non-small cell lung cancer (NSCLC) with KRAS G12C mutation. It is approved for medical use for this indication.
Population pharmacokinetic parameters in adult patients with advanced solid tumors (predominantly NSCLC), both sexes, median age ~65 years.