.Pharmacolibrary.Drugs.ATC.L.L02AE01_1

Information

name:Buserelin_1
ATC code:L02AE01_1
route:intranasal
compartments:2
dosage:1mg
volume of distribution:29.1L
clearance:1.16L/min
other parameters in model implementation

Buserelin is a synthetic analogue of the gonadotropin-releasing hormone (GnRH) used primarily in the treatment of hormone-sensitive cancers such as prostate cancer, endometriosis, and occasionally in assisted reproduction. It acts as a GnRH agonist, causing downregulation of pituitary secretion of gonadotropins and subsequent reduction in sex steroid production. The drug is approved and in current clinical use.

Pharmacokinetics

Pharmacokinetic parameters in healthy male volunteers after single intranasal administration.

References

    Revisions


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