.Pharmacolibrary.Drugs.ATC.L.L02AE05 .Pharmacolibrary.Drugs.ATC.L.L02AE05| name: | Histrelin | |
| ATC code: | L02AE05 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 1 | mg |
| volume of distribution: | 44.1 | L |
| clearance: | 11 | L/h |
| other parameters in model implementation | ||
Histrelin is a potent gonadotropin-releasing hormone (GnRH) agonist used primarily in the treatment of hormone-sensitive conditions such as central precocious puberty in children and advanced prostate cancer in adults. It is typically delivered as a subcutaneous implant for sustained drug release and is approved for these indications.
Pharmacokinetic parameters derived in adult healthy male subjects after a single intravenous infusion of histrelin.