name: | Aminoglutethimide |
ATC code: | L02BG01 | route: | oral |
n-compartments | 1 |
Aminoglutethimide is a nonsteroidal aromatase inhibitor and adrenal steroidogenesis inhibitor, formerly used to treat hormone-sensitive cancers such as advanced breast cancer and Cushing's syndrome. It is not frequently used in clinical practice today, having been largely replaced by more selective agents.
Pharmacokinetic parameters reported for healthy volunteers and patients with advanced cancer following oral administration, data reflect mixed-sex adult populations.