.Pharmacolibrary.Drugs.ATC.L.L03AX07 .Pharmacolibrary.Drugs.ATC.L.L03AX07| name: | PolyIC |
| ATC code: | L03AX07 | route: | intravenous |
| n-compartments | 1 |
Polyinosinic:polycytidylic acid (poly I:C) is a synthetic analog of double-stranded RNA, recognized as a mimic of viral genetic material. It activates the immune system primarily via Toll-like receptor 3 (TLR3), stimulating interferon production and modulating immune responses. Poly I:C has been used experimentally as an immunostimulant in cancer therapy and as a research tool to model viral infection. It is not approved as a marketed drug in clinical use currently.
No human pharmacokinetic studies are available for poly I:C; the following estimates are based on preclinical literature and structural similarity to other large RNA molecules. Poly I:C is typically administered by intravenous or intraperitoneal injection.