.Pharmacolibrary.Drugs.ATC.L.L04AJ01 .Pharmacolibrary.Drugs.ATC.L.L04AJ01| name: | Eculizumab |
| ATC code: | L04AJ01 | route: | intravenous |
| n-compartments | 2 |
Eculizumab is a monoclonal antibody that binds to complement protein C5, inhibiting terminal complement activation. It is used for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), refractory generalized myasthenia gravis, and neuromyelitis optica spectrum disorder. The drug is approved and in clinical use.
Pharmacokinetics reported in adult patients with paroxysmal nocturnal hemoglobinuria (PNH) after intravenous infusion.
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