.Pharmacolibrary.Drugs.ATC.L.L04AX03_1 .Pharmacolibrary.Drugs.ATC.L.L04AX03_1| name: | Methotrexate_1 |
| ATC code: | L04AX03_1 | route: | oral |
| n-compartments | 1 |
Methotrexate is an antimetabolite and antifolate drug, widely used in the treatment of various cancers (e.g., leukemia, lymphoma, breast cancer) and autoimmune diseases such as rheumatoid arthritis and psoriasis. It inhibits dihydrofolate reductase, blocking DNA synthesis and cell replication. Methotrexate is approved and used in clinical practice today for both oncological and non-oncological indications.
Pharmacokinetic parameters after oral administration in adult patients with rheumatoid arthritis. Oral bioavailability varies.
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