.Pharmacolibrary.Drugs.ATC.M.M01AE18 .Pharmacolibrary.Drugs.ATC.M.M01AE18| name: | Naproxcinod |
| ATC code: | M01AE18 | route: | oral |
| n-compartments | 1 |
Naproxcinod is a nitric oxide-donating prodrug of naproxen, developed as an anti-inflammatory and analgesic agent for the treatment of osteoarthritis and other musculoskeletal disorders. It was investigated as a potentially safer NSAID, aiming to reduce gastrointestinal and cardiovascular side effects. As of now, naproxcinod is not approved for use in any major regulatory jurisdiction and remains an investigational compound.
No published human pharmacokinetic models are available; parameters provided below are coarse estimates based on analogies to naproxen and existing public reports on naproxcinod in healthy adult subjects after oral administration.