name: | Bucillamine |
ATC code: | M01CC02 | route: | oral |
n-compartments | 1 |
Bucillamine is a disease-modifying antirheumatic drug (DMARD) structurally related to D-penicillamine. It is primarily used in Japan and South Korea for the treatment of rheumatoid arthritis and is not approved in most other countries. Bucillamine exerts anti-inflammatory and immunomodulatory effects, serving as a thiol donor with antioxidant properties.
Pharmacokinetic parameters estimated for healthy adult population, oral administration, based on analogies with D-penicillamine and available clinical summaries in Japanese prescribing information sources. No direct publication of detailed PK parameter values was found in the literature.