.Pharmacolibrary.Drugs.ATC.M.M02AA07

Information

Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class, used to relieve the symptoms of painful, inflammatory conditions like osteoarthritis and rheumatoid arthritis. It is an approved drug in many countries and is usually administered orally.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult subjects after a single oral dose.

References

1. Palma-Aguirre, JA, et al., & González-de la Parra, M (2010). Relative bioavailability of two oral formulations of piroxicam 20 mg: a single-dose, randomized-sequence, open-label, two-period crossover comparison in healthy Mexican adult volunteers. Clinical therapeutics 32(2) 357–364. DOI:10.1016/j.clinthera.2010.02.002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20206793

2. Calvo, AM, et al., & Santos, CF (2016). Effective method for the detection of piroxicam in human plasma using HPLC. Brazilian oral research 30(1) –. DOI:10.1590/1807-3107BOR-2016.vol30.0058 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27223141

3. Mailhot, C, et al., & Ward, JR (1986). The effect of cimetidine on serum concentrations of piroxicam. Pharmacotherapy 6(3) 112–117. DOI:10.1002/j.1875-9114.1986.tb03464.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/3488542

Revisions

• 06/2025 initial generated model