name: | Ketoprofen |
ATC code: | M02AA10 | route: | oral |
n-compartments | 2 |
Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and mild to moderate pain. It can be administered orally, topically, or parenterally. Ketoprofen is approved and used in many countries for pain management and as an anti-inflammatory agent.
Pharmacokinetic parameters reported in healthy adult volunteers after a single oral dose.
Rodríguez, MJ, et al., & Amaro, SR (2008). Dexketoprofen trometamol: clinical evidence supporting its role as a painkiller. Expert review of neurotherapeutics 8(11) 1625–1640. DOI:10.1586/14737175.8.11.1625 PUBMED:https://pubmed.ncbi.nlm.nih.gov/18986233
Rother, M, et al., & Mazgareanu, S (2007). Efficacy and safety of epicutaneous ketoprofen in Transfersome (IDEA-033) versus oral celecoxib and placebo in osteoarthritis of the knee: multicentre randomised controlled trial. Annals of the rheumatic diseases 66(9) 1178–1183. DOI:10.1136/ard.2006.065128 PUBMED:https://pubmed.ncbi.nlm.nih.gov/17363401
Fourie, T, et al., & Naidoo, V (2015). The Safety and Pharmacokinetics of Carprofen, Flunixin and Phenylbutazone in the Cape Vulture (Gyps coprotheres) following Oral Exposure. PloS one 10(10) e0141419–None. DOI:10.1371/journal.pone.0141419 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26512724