.Pharmacolibrary.Drugs.ATC.M.M02AA13_1 .Pharmacolibrary.Drugs.ATC.M.M02AA13_1| name: | Ibuprofen_1 |
| ATC code: | M02AA13_1 | route: | intravenous |
| n-compartments | 2 |
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely used for its analgesic, antipyretic, and anti-inflammatory effects. It is commonly used for the treatment of mild to moderate pain, inflammation, and fever. Ibuprofen is an over-the-counter medication and is approved for clinical use worldwide.
Pharmacokinetic parameters reported for healthy adults after a single intravenous administration.
Jin, Y, et al., & Wang, Z (2023). Comparison of intravenous ibuprofen pharmacokinetics between Caucasian and Chinese populations using physiologically based pharmacokinetics modeling and simulation. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 191 106587–None. DOI:10.1016/j.ejps.2023.106587 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37734467
Zhou, H, et al., & Liu, Y (2016). Pharmacokinetics and tolerability of intravenous ibuprofen injection in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study . International journal of clinical pharmacology and therapeutics 54(11) 904–913. DOI:10.5414/CP202603 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27569737
Han, EE, et al., & Shapiro, BJ (2004). Pharmacokinetics of Ibuprofen in children with cystic fibrosis. Clinical pharmacokinetics 43(3) 145–156. DOI:10.2165/00003088-200443030-00001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/14871154