.Pharmacolibrary.Drugs.ATC.M.M02AA15

Information

name:Diclofenac
ATC code:M02AA15
route:oral
n-compartments2

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory disorders such as arthritis, musculoskeletal injuries, and postoperative pain. It is available in various formulations including oral, topical, and injectable. It is widely approved and in current clinical use worldwide.

Pharmacokinetics

Pharmacokinetics reported in healthy adult volunteers following a single oral dose.

References

  1. Moore, RA, et al., & Straube, S (2015). Effects of food on pharmacokinetics of immediate release oral formulations of aspirin, dipyrone, paracetamol and NSAIDs - a systematic review. British journal of clinical pharmacology 80(3) 381–388. DOI:10.1111/bcp.12628 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25784216

  2. Standing, JF, et al., & Wong, IC (2008). Population pharmacokinetics of oral diclofenac for acute pain in children. British journal of clinical pharmacology 66(6) 846–853. DOI:10.1111/j.1365-2125.2008.03289.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/19032726

  3. Lötsch, J, et al., & Kobal, G (2000). Population pharmacokinetics of fast release oral diclofenac in healthy volunteers: relation to pharmacodynamics in an experimental pain model. Pharmaceutical research 17(1) 77–84. DOI:10.1023/a:1007574710140 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10714612

Revisions


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