.Pharmacolibrary.Drugs.ATC.M.M02AA27 .Pharmacolibrary.Drugs.ATC.M.M02AA27| name: | Dexketoprofen |
| ATC code: | M02AA27 | route: | oral |
| n-compartments | 1 |
Dexketoprofen is the (S)-enantiomer of ketoprofen, belonging to the non-steroidal anti-inflammatory drug (NSAID) class. It is used for the short-term treatment of mild to moderate acute pain, including musculoskeletal pain and dysmenorrhea. Dexketoprofen is approved for use in several countries.
Pharmacokinetic parameters reported in healthy male and female volunteers after administration of a single oral dose.
Rodríguez, MJ, et al., & Amaro, SR (2008). Dexketoprofen trometamol: clinical evidence supporting its role as a painkiller. Expert review of neurotherapeutics 8(11) 1625–1640. DOI:10.1586/14737175.8.11.1625 PUBMED:https://pubmed.ncbi.nlm.nih.gov/18986233
Valles, J, et al., & Capriati, A (2006). Single and repeated dose pharmacokinetics of dexketoprofen trometamol in young and elderly subjects. Methods and findings in experimental and clinical pharmacology 28 Suppl A 13–19. PUBMED:https://pubmed.ncbi.nlm.nih.gov/16801988
Varrassi, G, et al., & Scarpignato, C (2017). Multimodal analgesia in moderate-to-severe pain: a role for a new fixed combination of dexketoprofen and tramadol. Current medical research and opinion 33(6) 1165–1173. DOI:10.1080/03007995.2017.1310092 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28326850