.Pharmacolibrary.Drugs.ATC.M.M02AA31

Information

name:Loxoprofen
ATC code:M02AA31
route:oral
compartments:2
dosage:60mg
volume of distribution:9.77L
clearance:5.59L/h
other parameters in model implementation

Loxoprofen is a non-steroidal anti-inflammatory drug (NSAID) used for the relief of pain and inflammation in conditions such as musculoskeletal disorders, osteoarthritis, and postoperative pain. It is primarily approved in Japan and some other Asian countries but is not approved by the FDA in the United States.

Pharmacokinetics

Pharmacokinetics in healthy adult Japanese volunteers after a single oral dose.

References

  1. Kim, TH, et al., & Shin, BS (2017). Development of a Physiologically Relevant Population Pharmacokinetic in Vitro-in Vivo Correlation Approach for Designing Extended-Release Oral Dosage Formulation. Molecular pharmaceutics 14(1) 53–65. DOI:10.1021/acs.molpharmaceut.6b00677 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27809538

Revisions


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