.Pharmacolibrary.Drugs.ATC.M.M04AA51

Information

name:AllopurinolCombinations
ATC code:M04AA51
route:oral
compartments:1
dosage:300mg
volume of distribution:1.6L
clearance:126ml/min
other parameters in model implementation

Allopurinol in combination with other agents is used primarily to treat gout and hyperuricemia by reducing uric acid production. It acts as a xanthine oxidase inhibitor. Some combinations may also contain agents that facilitate uric acid excretion or mitigate adverse effects. Allopurinol and its combinations are approved and commonly used in clinical practice.

Pharmacokinetics

PK parameters estimated for typical adult population, oral administration. No specific individual, sex, age, or co-morbidity differentiation. Parameters are estimates based on known single agent allopurinol models, as no published PK model exists for combinations.

References

    Revisions


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