.Pharmacolibrary.Drugs.ATC.M.M04AB01 .Pharmacolibrary.Drugs.ATC.M.M04AB01| name: | Probenecid |
| ATC code: | M04AB01 | route: | oral |
| n-compartments | 1 |
Probenecid is a uricosuric agent primarily used for the treatment of hyperuricemia associated with gout and gouty arthritis. The drug acts by inhibiting the renal tubular reabsorption of uric acid, thereby increasing its excretion. It is also known to increase plasma concentrations of some antibiotics (e.g., penicillins, cephalosporins) by inhibiting their renal excretion. Probenecid is an approved drug and in clinical use, though less commonly used today given the availability of newer agents.
Pharmacokinetic parameters in healthy adult volunteers following single oral dose administration.
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