.Pharmacolibrary.Drugs.ATC.M.M05BA06

Information

name:IbandronicAcid
ATC code:M05BA06
route:intravenous
n-compartments2

Ibandronic acid (ibandronate) is a bisphosphonate drug used primarily for the prevention and treatment of osteoporosis in postmenopausal women. It reduces bone resorption by inhibiting osteoclast-mediated bone loss. Ibandronic acid is approved for clinical use in several countries as both oral and intravenous formulations.

Pharmacokinetics

Pharmacokinetic parameters in healthy postmenopausal women after a single intravenous dose.

References

  1. Croom, KF, & Scott, LJ (2006). Intravenous ibandronate: in the treatment of osteoporosis. Drugs 66(12) 1593–1603. DOI:10.2165/00003495-200666120-00005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/16956306

  2. Pillai, G, et al., & Steimer, JL (2006). Population pharmacokinetics of ibandronate in Caucasian and Japanese healthy males and postmenopausal females. International journal of clinical pharmacology and therapeutics 44(12) 655–667. DOI:10.5414/cpp44655 PUBMED:https://pubmed.ncbi.nlm.nih.gov/17190376

  3. Nakai, K, et al., & Kawanishi, T (2016). The optimal oral dose selection of ibandronate in Japanese patients with osteoporosis based on pharmacokinetic and pharmacodynamic properties. European journal of drug metabolism and pharmacokinetics 41(2) 139–147. DOI:10.1007/s13318-014-0242-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25476995

Revisions


Generated at 2025-07-20T18:21:09Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos