.Pharmacolibrary.Drugs.ATC.M.M05BB03

Information

name:AlendronicAcidAndColecalciferol
ATC code:M05BB03
route:oral
compartments:1
dosage:70mg
volume of distribution:28L
clearance:200ml/min
other parameters in model implementation

Alendronic acid (alendronate) is a bisphosphonate used to treat and prevent osteoporosis by inhibiting bone resorption, while colecalciferol (vitamin D3) is essential for calcium absorption and bone health. The combination is approved and indicated for osteoporosis in postmenopausal women and men at risk of vitamin D deficiency.

Pharmacokinetics

Pharmacokinetic parameters estimated from data for individual components; alendronate PK parameters are based on healthy adult volunteers following oral administration. Colecalciferol PK parameters are not routinely reported when co-administered with alendronate, and specific combination PK studies are lacking.

References

    Revisions


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