.Pharmacolibrary.Drugs.ATC.M.M05BB05 .Pharmacolibrary.Drugs.ATC.M.M05BB05| name: | AlendronicAcidCalciumAndColecalciferolSequential |
| ATC code: | M05BB05 | route: | oral |
| n-compartments | 1 |
A fixed combination regimen used for the treatment and prevention of osteoporosis in adults, particularly postmenopausal women and older men. Alendronic acid is a bisphosphonate that inhibits bone resorption, calcium is essential for bone mineralization, and colecalciferol (vitamin D3) improves calcium absorption. This combination provides a comprehensive approach to bone health. The sequential regimen is approved and in clinical use for osteoporosis management.
No published pharmacokinetic studies reporting population PK parameters for the fixed sequential combination of alendronic acid, calcium, and colecalciferol. Single-agent data were used to estimate parameters: healthy adults, both sexes, typical oral dose.