.Pharmacolibrary.Drugs.ATC.M.M05BB05

Information

name:AlendronicAcidCalciumAndColecalciferolSequential
ATC code:M05BB05
route:oral
compartments:1
dosage:70mg
volume of distribution:28L
clearance:120mL/min
other parameters in model implementation

A fixed combination regimen used for the treatment and prevention of osteoporosis in adults, particularly postmenopausal women and older men. Alendronic acid is a bisphosphonate that inhibits bone resorption, calcium is essential for bone mineralization, and colecalciferol (vitamin D3) improves calcium absorption. This combination provides a comprehensive approach to bone health. The sequential regimen is approved and in clinical use for osteoporosis management.

Pharmacokinetics

No published pharmacokinetic studies reporting population PK parameters for the fixed sequential combination of alendronic acid, calcium, and colecalciferol. Single-agent data were used to estimate parameters: healthy adults, both sexes, typical oral dose.

References

    Revisions


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