.Pharmacolibrary.Drugs.ATC.M.M05BB06

Information

name:AlendronicAcidAndAlfacalcidolSequential
ATC code:M05BB06
route:oral
compartments:1
dosage:70mg
volume of distribution:28L
clearance:11L/hr
other parameters in model implementation

This combination drug contains alendronic acid, a bisphosphonate used to treat osteoporosis by inhibiting bone resorption, and alfacalcidol, a vitamin D analog facilitating calcium absorption. The sequential administration is intended for the management of osteoporosis and related bone disorders in adults and is a therapy available in some regions, though combination regimens may not be globally standard.

Pharmacokinetics

Estimated pharmacokinetic model parameters for adults, both sexes, typical of osteoporotic populations. Parameters are based on reported data for individual components as pharmacokinetic data for the combination product is not available in scientific literature.

References

    Revisions


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