.Pharmacolibrary.Drugs.ATC.M.M05BX07 .Pharmacolibrary.Drugs.ATC.M.M05BX07| name: | Vosoritide |
| ATC code: | M05BX07 | route: | subcutaneous |
| n-compartments | 1 |
Vosoritide is a recombinant human C-type natriuretic peptide (CNP) analogue indicated for the treatment of achondroplasia in patients who are aged 2 years and older with open epiphyses. It is approved for use in several regions, including the US and EU. Vosoritide acts as a growth modulator by binding to natriuretic peptide receptor NPR-B (NPR2), stimulating endochondral bone growth.
Pharmacokinetic parameters reported in pediatric subjects (age 5-14 years) with achondroplasia after daily subcutaneous administration of vosoritide. The model assumes a one-compartment disposition.