.Pharmacolibrary.Drugs.ATC.M.M09AX11

Information

name:Palovarotene
ATC code:M09AX11
route:oral
compartments:2
dosage:10mg
volume of distribution:282L
clearance:13.6L/h
other parameters in model implementation

Palovarotene is a selective retinoic acid receptor gamma (RARĪ³) agonist developed for the treatment of fibrodysplasia ossificans progressiva (FOP), a rare genetic disorder involving heterotopic ossification. As of 2023, palovarotene is approved in some regions for FOP and used under clinical investigation in others.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after oral administration of single and multiple doses.

References

    Revisions

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