.Pharmacolibrary.Drugs.ATC.N.N01AX05_2

Information

name:Alfaxalone_2
ATC code:N01AX05_2
route:intravenous
n-compartments2

Alfaxalone is a neuroactive steroid anesthetic for veterinary use, acting primarily via potentiation of GABAergic neurotransmission; used for induction and maintenance of anesthesia in small animals.

Pharmacokinetics

No human pharmacokinetic data published; estimates in humans based on allometric scaling from animal data.

References

  1. Pypendop, BH, et al., & Pasloske, K (2018). Pharmacokinetics of alfaxalone infusions, context-sensitive half-time and recovery times in male neutered cats. Veterinary anaesthesia and analgesia 45(5) 630–639. DOI:10.1016/j.vaa.2018.06.003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30057008

  2. Pypendop, BH, et al., & Pasloske, K (2018). Effective plasma alfaxalone concentration to produce immobility in male neutered cats. Veterinary anaesthesia and analgesia 45(3) 269–277. DOI:10.1016/j.vaa.2017.10.006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29415861

Revisions

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