.Pharmacolibrary.Drugs.ATC.N.N01BB51 .Pharmacolibrary.Drugs.ATC.N.N01BB51| name: | BupivacaineCombinations |
| ATC code: | N01BB51 | route: | epidural |
| n-compartments | 2 |
Bupivacaine is a long-acting local anesthetic belonging to the amide-type class, often used for regional anesthesia, including epidural, spinal, and peripheral nerve blocks. It acts by blocking sodium channels, thereby inhibiting nerve impulse propagation. As a combination product (ATC N01BB51), it is typically formulated with other anesthetics or analgesics for surgical anesthesia and pain management. Bupivacaine is approved and widely used in various clinical settings today.
Pharmacokinetic parameters reported for healthy adult patients, mixed sex, receiving epidural administration of bupivacaine as part of a combination preparation.
Chalkiadis, GA, et al., & Anderson, BJ (2013). Absorption characteristics of epidural levobupivacaine with adrenaline and clonidine in children. Paediatric anaesthesia 23(1) 58–67. DOI:10.1111/pan.12074 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23167288