.Pharmacolibrary.Drugs.ATC.N.N02AA05

Information

name:Oxycodone
ATC code:N02AA05
route:oral
n-compartments2

Oxycodone is a semi-synthetic opioid analgesic used for the management of moderate to severe pain. It is a controlled substance, approved for medical use in many countries and commonly prescribed for post-operative pain, cancer pain, and chronic pain conditions.

Pharmacokinetics

Pharmacokinetic parameters from healthy adult male and female volunteers following a single oral dose administration.

References

  1. Lugo, RA, & Kern, SE (2004). The pharmacokinetics of oxycodone. Journal of pain & palliative care pharmacotherapy 18(4) 17–30. DOI:10.1300/j354v18n04_03 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15760805

  2. Agema, BC, et al., & Koolen, SLW (2021). Population Pharmacokinetics of Oxycodone and Metabolites in Patients with Cancer-Related Pain. Cancers 13(11) –. DOI:10.3390/cancers13112768 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34199534

  3. Thigpen, JC, et al., & Harirforoosh, S (2019). Opioids: A Review of Pharmacokinetics and Pharmacodynamics in Neonates, Infants, and Children. European journal of drug metabolism and pharmacokinetics 44(5) 591–609. DOI:10.1007/s13318-019-00552-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31006834

Revisions

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