.Pharmacolibrary.Drugs.ATC.N.N02AA56 .Pharmacolibrary.Drugs.ATC.N.N02AA56| name: | OxycodoneAndNaltrexone |
| ATC code: | N02AA56 | route: | oral |
| n-compartments | 1 |
Oxycodone and naltrexone is a fixed-dose combination medication used for the management of severe pain where an opioid analgesic is appropriate and abuse deterrence is needed. Oxycodone is an opioid agonist used for pain relief, while naltrexone is an opioid antagonist included to mitigate risk of abuse. The combination is marketed in certain formulations (e.g., extended-release tablets) with regulatory approval in some countries, but is not universally available worldwide.
No published pharmacokinetic models directly reporting PK parameters for the fixed-dose oxycodone and naltrexone combination tablet were found. The data below are estimated based on available PK data for oxycodone and naltrexone individually in healthy adults after oral administration.
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