.Pharmacolibrary.Drugs.ATC.N.N02AA59 .Pharmacolibrary.Drugs.ATC.N.N02AA59| name: | CodeineCombinationsExclPsycholeptics | |
| ATC code: | N02AA59 | route: | oral |
| compartments: | 1 | |
| dosage: | 30 | mg |
| volume of distribution: | 3.5 | L |
| clearance: | 21.6 | L/h |
| other parameters in model implementation | ||
Codeine is an opioid analgesic commonly used for the relief of mild to moderate pain and to suppress cough. In combinations excluding psycholeptics, it is often combined with other non-opioid analgesics such as paracetamol or ibuprofen to enhance analgesic efficacy. It is approved and available in many countries, although subject to increasing regulatory controls due to opioid misuse risk.
Pharmacokinetic parameters are described for healthy adult subjects (both sexes) after a single oral dose of codeine combination product.