.Pharmacolibrary.Drugs.ATC.N.N02AB01 .Pharmacolibrary.Drugs.ATC.N.N02AB01| name: | Ketobemidone | |
| ATC code: | N02AB01 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 10 | mg |
| volume of distribution: | 2.5 | L |
| clearance: | 50 | mL/min/kg |
| other parameters in model implementation | ||
Ketobemidone is an opioid analgesic drug used mostly in Scandinavian countries for the management of moderate to severe pain. It acts as an agonist at the mu-opioid receptor and also exhibits NMDA antagonist properties. It is not approved for use in the United States or many other countries.
Pharmacokinetic parameters reported for healthy adult volunteers after intravenous administration.
Lundeberg, S, et al., & Eksborg, S (2012). Pharmacokinetics after a single intravenous dose of the opioid ketobemidone in neonates. Acta anaesthesiologica Scandinavica 56(8) 1026–1031. DOI:10.1111/j.1399-6576.2012.02726.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/22834454