.Pharmacolibrary.Drugs.ATC.N.N02AG02 .Pharmacolibrary.Drugs.ATC.N.N02AG02| name: | KetobemidoneAndAntispasmodics | |
| ATC code: | N02AG02 | route: | oral |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 1.8 | L |
| clearance: | 1.0 | L/min |
| other parameters in model implementation | ||
Combination preparations of ketobemidone (a synthetic opioid analgesic) with antispasmodic agents (such as hyoscine) were formerly used for pain with spastic components, including renal or biliary colic. Ketobemidone acts as a mu-opioid receptor agonist with analgesic effects, while antispasmodics help reduce smooth muscle spasms. This combination is not widely used or approved today in many countries.
No published pharmacokinetic parameters are available for the combination 'ketobemidone and antispasmodics' (N02AG02) in the literature; parameters below are estimated based on data from ketobemidone alone in healthy adults.