.Pharmacolibrary.Drugs.ATC.N.N02BA01

Information

name:AcetylsalicylicAcid
ATC code:N02BA01
route:oral
compartments:1
dosage:500mg
volume of distribution:0.16L
clearance:40L/h
other parameters in model implementation

Acetylsalicylic acid, commonly known as aspirin, is a nonsteroidal anti-inflammatory drug (NSAID) used primarily as an analgesic, antipyretic, and anti-inflammatory agent. It is also used as an antiplatelet agent for the prevention of cardiovascular events such as myocardial infarction and stroke. Aspirin is approved and widely used today for these indications.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult volunteers, following a single oral dose.

References

  1. Fager, G, et al., & Eriksson, UG (2003). Pharmacokinetics and pharmacodynamics of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, are not influenced by acetylsalicylic acid. European journal of clinical pharmacology 59(4) 283–289. DOI:10.1007/s00228-003-0619-x PUBMED:https://pubmed.ncbi.nlm.nih.gov/12845508

  2. Brouwers, JR, & de Smet, PA (1994). Pharmacokinetic-pharmacodynamic drug interactions with nonsteroidal anti-inflammatory drugs. Clinical pharmacokinetics 27(6) 462–485. DOI:10.2165/00003088-199427060-00005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7882636

  3. Stephen, LJ (2003). Drug treatment of epilepsy in elderly people: focus on valproic Acid. Drugs & aging 20(2) 141–152. DOI:10.2165/00002512-200320020-00005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12534314

Revisions


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