name: | Gabapentin |
ATC code: | N02BF01 | route: | oral |
n-compartments | 1 |
Gabapentin is an anticonvulsant medication primarily used to treat neuropathic pain and partial seizures. It is also approved for the management of postherpetic neuralgia and is widely used off-label for various pain syndromes and anxiety disorders. Gabapentin is currently approved and in clinical use in many countries.
Pharmacokinetic parameters derived from studies in healthy adult volunteers following a single oral dose.
Hampton, CE, et al., & Pypendop, BH (2021). Pharmacokinetics of oral and compounded intravenous gabapentin in Duroc swine (Sus Scrofa). Journal of veterinary pharmacology and therapeutics 44(5) 776–782. DOI:10.1111/jvp.12977 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33978255
Adrian, D, et al., & Lascelles, BDX (2018). The pharmacokinetics of gabapentin in cats. Journal of veterinary internal medicine 32(6) 1996–2002. DOI:10.1111/jvim.15313 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30307652
Tran, P, et al., & Lee, YB (2017). Population pharmacokinetics of gabapentin in healthy Korean subjects with influence of genetic polymorphisms of ABCB1. Journal of pharmacokinetics and pharmacodynamics 44(6) 567–579. DOI:10.1007/s10928-017-9549-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29018999