.Pharmacolibrary.Drugs.ATC.N.N02BF01

Information

name:Gabapentin
ATC code:N02BF01
route:oral
n-compartments1

Gabapentin is an anticonvulsant medication primarily used to treat neuropathic pain and partial seizures. It is also approved for the management of postherpetic neuralgia and is widely used off-label for various pain syndromes and anxiety disorders. Gabapentin is currently approved and in clinical use in many countries.

Pharmacokinetics

Pharmacokinetic parameters derived from studies in healthy adult volunteers following a single oral dose.

References

  1. Hampton, CE, et al., & Pypendop, BH (2021). Pharmacokinetics of oral and compounded intravenous gabapentin in Duroc swine (Sus Scrofa). Journal of veterinary pharmacology and therapeutics 44(5) 776–782. DOI:10.1111/jvp.12977 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33978255

  2. Adrian, D, et al., & Lascelles, BDX (2018). The pharmacokinetics of gabapentin in cats. Journal of veterinary internal medicine 32(6) 1996–2002. DOI:10.1111/jvim.15313 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30307652

  3. Tran, P, et al., & Lee, YB (2017). Population pharmacokinetics of gabapentin in healthy Korean subjects with influence of genetic polymorphisms of ABCB1. Journal of pharmacokinetics and pharmacodynamics 44(6) 567–579. DOI:10.1007/s10928-017-9549-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29018999

Revisions


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