.Pharmacolibrary.Drugs.ATC.N.N02CA02 .Pharmacolibrary.Drugs.ATC.N.N02CA02| name: | Ergotamine | |
| ATC code: | N02CA02 | route: | oral |
| compartments: | 2 | |
| dosage: | 2 | mg |
| volume of distribution: | 8.4 | L |
| clearance: | 1.0 | L/min |
| other parameters in model implementation | ||
Ergotamine is an ergot alkaloid used for the acute treatment of migraine attacks and cluster headaches. It is a vasoconstrictor and acts by stimulating alpha-adrenergic and serotonergic (5-HT1) receptors. Use of ergotamine has declined due to the availability of triptans and its side effect profile. It is currently approved in some countries but less commonly used.
Pharmacokinetic parameters reported for healthy adult volunteers, both sexes, following a single oral dose.