.Pharmacolibrary.Drugs.ATC.N.N02CC51 .Pharmacolibrary.Drugs.ATC.N.N02CC51| name: | SumatriptanAndNaproxen |
| ATC code: | N02CC51 | route: | oral |
| n-compartments | 1 |
Sumatriptan and naproxen is a fixed-dose combination medication used for the acute treatment of migraine attacks, with or without aura, in adults. Sumatriptan is a selective 5-HT1B/1D receptor agonist causing cranial vessel constriction and inhibition of neuropeptide release, while naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain. The combination is FDA-approved and widely used in clinical practice.
Pharmacokinetic parameters for sumatriptan and naproxen fixed combination, in healthy adult subjects, following oral administration.