.Pharmacolibrary.Drugs.ATC.N.N03AD01

Information

name:Ethosuximide
ATC code:N03AD01
route:oral
n-compartments1

Ethosuximide is an anticonvulsant drug primarily used for the treatment of absence (petit mal) seizures, especially in children. It acts mainly by reducing low-threshold calcium currents in thalamic neurons. Ethosuximide is approved and commonly used in clinical practice for epilepsy management.

Pharmacokinetics

Pharmacokinetic parameters in healthy adults and children, based on oral administration.

References

  1. Eriksson, AS, et al., & Boreus, L (1996). Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy. Epilepsia 37(8) 769–773. DOI:10.1111/j.1528-1157.1996.tb00650.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/8764817

  2. Löscher, W, et al., & Schmidt, D (1985). Evaluation of epileptic dogs as an animal model of human epilepsy. Arzneimittel-Forschung 35(1) 82–87. PUBMED:https://pubmed.ncbi.nlm.nih.gov/4039156

Revisions

Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos