.Pharmacolibrary.Drugs.ATC.N.N03AF01

Information

name:Carbamazepine
ATC code:N03AF01
route:oral
n-compartments2

Carbamazepine is an anticonvulsant and mood-stabilizing drug primarily used for the treatment of epilepsy and neuropathic pain, as well as bipolar disorder. It is an approved medication used worldwide for controlling certain types of seizures, trigeminal neuralgia, and as an adjunct in the management of psychiatric disorders.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers following single oral dosing.

References

  1. Djordjevic, N, et al., & Milovanovic, JR (2017). Pharmacokinetics and Pharmacogenetics of Carbamazepine in Children. European journal of drug metabolism and pharmacokinetics 42(5) 729–744. DOI:10.1007/s13318-016-0397-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28064419

  2. El Desoky, ES, et al., & Derendorf, H (2012). Population pharmacokinetics of steady-state carbamazepine in Egyptian epilepsy patients. Journal of clinical pharmacy and therapeutics 37(3) 352–355. DOI:10.1111/j.1365-2710.2011.01296.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/21883329

  3. Elewa, M, et al., & Matar, K (2023). Population Pharmacokinetics of Topiramate in Patients with Epilepsy Using Nonparametric Modeling. Therapeutic drug monitoring 45(6) 797–804. DOI:10.1097/FTD.0000000000001143 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37798835

Revisions


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