.Pharmacolibrary.Drugs.ATC.N.N03AX14 .Pharmacolibrary.Drugs.ATC.N.N03AX14| name: | Levetiracetam | |
| ATC code: | N03AX14 | route: | oral |
| compartments: | 1 | |
| dosage: | 1000 | mg |
| volume of distribution: | 0.5 | L |
| clearance: | 0.96 | mL/min/kg |
| other parameters in model implementation | ||
Levetiracetam is an anticonvulsant medication used primarily for the treatment of epilepsy. It is indicated as adjunctive therapy for partial onset seizures, myoclonic seizures, and tonic-clonic seizures in adults and children. Levetiracetam is widely approved and used in clinical practice today.
Pharmacokinetic parameters reported in healthy adult subjects after oral administration.
Hernández-Mitre, MP, et al., & Milán-Segovia, RDC (2020). Population Pharmacokinetics and Dosing Recommendations of Levetiracetam in Adult and Elderly Patients With Epilepsy. Journal of pharmaceutical sciences 109(6) 2070–2078. DOI:10.1016/j.xphs.2020.02.018 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32113977
Zimmerman, KO, et al., & Hornik, CP (2023). Pharmacokinetics and Proposed Dosing of Levetiracetam in Children With Obesity. The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 28(8) 693–703. DOI:10.5863/1551-6776-28.8.693 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38094673