name: | Cannabidiol |
ATC code: | N03AX24 | route: | oral |
n-compartments | 2 |
Cannabidiol (CBD) is a non-psychoactive phytocannabinoid found in Cannabis sativa. It is used as an anticonvulsant for treatment of certain epileptic disorders such as Dravet syndrome and Lennox-Gastaut syndrome, and is an approved medication (as Epidiolex) in the United States and several other countries.
Pharmacokinetic parameters reported in healthy adult volunteers after oral administration of purified cannabidiol solution.
Schultz, HB, et al., & Reuter, SE (2023). Population Pharmacokinetics of Oral-Based Administration of Cannabidiol in Healthy Adults: Implications for Drug Development. Cannabis and cannabinoid research 8(5) 877–886. DOI:10.1089/can.2021.0202 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35443784
Gamble, LJ, et al., & Wakshlag, JJ (2018). Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs. Frontiers in veterinary science 5 165–None. DOI:10.3389/fvets.2018.00165 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30083539
Sánchez de Medina, A, et al., & Sánchez de Medina, V (2023). Pharmacokinetics and oral bioavailability of cannabidiol in horses after intravenous and oral administration with oil and micellar formulations. Equine veterinary journal 55(6) 1094–1103. DOI:10.1111/evj.13923 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36624043