name: | LevodopaAndDecarboxylaseInhibitor_1 |
ATC code: | N04BA02_1 | route: | oral |
n-compartments | 1 |
Levodopa and decarboxylase inhibitor is a combination drug used in the management of Parkinson's disease. Levodopa is a precursor of dopamine, which is deficient in patients with Parkinson's disease, and the decarboxylase inhibitor (usually carbidopa) prevents the peripheral breakdown of levodopa, increasing its availability to the brain. This therapy is widely used and approved in clinical practice.
Pharmacokinetic parameters for healthy adults receiving single oral dose of levodopa/carbidopa (100 mg/25 mg).
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