name: | Acepromazine_1 |
ATC code: | N05AA04_1 | route: | oral |
n-compartments | 2 |
Acepromazine is a phenothiazine derivative used primarily as a veterinary tranquilizer and sedative. It is commonly administered to dogs, cats, and horses for pre-anesthetic sedation, prevention of motion sickness, or for general tranquilization. Its use in humans is extremely rare today and primarily limited to veterinary medicine.
Pharmacokinetic parameters for acepromazine in healthy adult dogs after oral administration.
Knych, HK, et al., & Kass, PH (2018). Pharmacokinetics, pharmacodynamics, and metabolism of acepromazine following intravenous, oral, and sublingual administration to exercised Thoroughbred horses. Journal of veterinary pharmacology and therapeutics 41(4) 522–535. DOI:10.1111/jvp.12494 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29457257